Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 166
interventional 103
Observational 61
Registry 2

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 46
Device 12
Other 12
Drug|placebo 6
Diagnostic Test 4
Drug|Other 4
Procedure 4
Biological|placebo 2
Drug|Procedure 2
Behavioral 1
Behavioral|Device 1
Behavioral|Device|Other 1
Behavioral|Drug|Other 1
Biological|Drug|placebo 1
Device|Drug 1
Device|Other 1
Dietary Supplement|Drug 1
Genetic 1
Other|Procedure 1
placebo|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 30
NA 9
Canada 7
France 6
Belgium 5
Spain 5
Denmark 3
Israel 3
Korea, Republic of 3
Australia 2
Brazil 2
Germany 2
Switzerland 2
Austria 1
Bahrain|Kuwait|Lebanon|Oman|Qatar 1
Belgium|Italy|Portugal|Slovenia|Spain|United Kingdom 1
Colombia 1
Czech Republic 1
Germany|Switzerland 1
India 1
Israel|Italy 1
Japan 1
Netherlands 1
Portugal|Spain 1
Singapore 1
Sweden 1
Thailand 1
United Kingdom 1
United States|Argentina|Brazil|Bulgaria|Georgia|Germany|Israel|Italy|Russian Federation|Spain|Ukraine 1
United States|Argentina|Brazil|Colombia|Greece|Israel|Italy|United Kingdom 1
United States|Australia|Canada|Israel|New Zealand|Saudi Arabia 1
United States|Belarus|Brazil|China|Greece|Hungary|India|Israel|Korea, Republic of|Lithuania|Mexico|Peru|Russian Federation|Taiwan|Thailand|Turkey 1
United States|Belgium|Bulgaria|Chile|Czechia|France|Germany|Greece|Guatemala|Israel|Italy|Russian Federation|Spain|United Kingdom 1
United States|Canada 1
United States|Korea, Republic of|Spain 1
United States|Spain 1
Zambia 1

Sites per Study

Site_count Study_Count
1 59
2 15
3 3
4 3
5 1
6 1
7 2
12 1
13 1
14 1
15 1
16 2
17 1
18 1
21 1
22 1
27 1
33 1
43 1
44 1
50 1
51 1
72 1
78 1
92 1

Phase

Phase Study_Count
N/A 44
Phase 4 25
Phase 3 14
Phase 2 11
Phase 1 4
Phase 1/Phase 2 2
Phase 2/Phase 3 2
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 13
2 59
3 4
4 9
5 1
6 1
NA 16

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 43 10.000 18.00 40 18.00 440.00 66.000 15.0
1st Qu. 43 105.500 19.50 43 52.50 724.75 129.000 56.0
Median 43 266.000 23.50 46 77.00 1009.50 344.000 200.0
Mean 43 1287.326 68.25 46 142.80 1009.50 1015.462 327.8
3rd Qu. 43 746.500 72.25 49 169.75 1294.25 450.000 400.0
Max. 43 14889.000 208.00 52 509.00 1579.00 8665.000 1600.0

Trial Group Type

group_type Group_Count
Experimental 87
Active Comparator 66
NA 16
Placebo Comparator 13
No Intervention 12
Other 12

Intervention Model

intervention_model Study_Count
Parallel Assignment 68
Single Group Assignment 17
Crossover Assignment 8
NA 6
Factorial Assignment 4

Primary Purpose

primary_purpose Study_Count
Treatment 55
Prevention 29
Diagnostic 14
NA 2
Basic Science 1
Other 1
Supportive Care 1

Observational Studies

Studies by Country

Country Study_Count
United States 24
Spain 6
Israel 4
NA 3
Austria 2
China 2
France 2
Thailand 2
Bangladesh|Kenya|Malawi|Pakistan|Uganda 1
Belgium 1
Burkina Faso 1
Finland 1
Germany 1
Germany|Italy|United Kingdom 1
Italy 1
Korea, Republic of 1
Myanmar 1
Netherlands 1
Saudi Arabia 1
Switzerland 1
Taiwan 1
Turkey 1
United States|Canada 1
United States|Greece|Italy|United Kingdom 1

Sites per Study

Site_count Study_Count
1 40
2 3
3 4
4 1
5 1
6 1
7 1
8 1
14 2
15 1
16 1
17 1
21 1
22 2
29 1

Enrollment Metrics

Measure Observational
Min 1.00
1st Qu 150.00
Median 500.00
Mean 99394.56
3rd Qu 1064.00
Max 6000000.00

Observation Model

observational_model Study_Count
Cohort 36
Other 7
Case Control 6
Case-Only 5
NA 3
Ecologic or Community 2
Case-Crossover 1
Defined Population, Natural History 1

Time Perspective

time_perspective Study_Count
Prospective 42
Retrospective 15
Other 2
Cross-Sectional 1
Longitudinal, Retrospective 1

Registries

Studies by Country

Country Study_Count
Australia|France 1
United States|Argentina|Chile|Germany|Spain 1

Sites per Study

Site_count Study_Count
2 1
12 1

Enrollment Metrics

Measure Registries
Min 1000
1st Qu 1500
Median 2000
Mean 2000
3rd Qu 2500
Max 3000

Registry Model

observational_model Study_Count
Cohort 2

Time Perspective

time_perspective Study_Count
Prospective 2

Follow-up

target_duration Study_Count
28 Days 1
30 Days 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT01919593 Efficacy of 2% Chlorhexidine Gluconate in 70% Alcohol Compare 10% Povidone Iodine in Blood Culture in Children https://ClinicalTrials.gov/show/NCT01919593 Completed Thammasat University 2012-12-31
NCT01191840 Treatment Algorithm to Reduce the Use of Vancomycin in Adults With Blood Stream Infection https://ClinicalTrials.gov/show/NCT01191840 Completed Duke University 2017-03-04
NCT03309137 Device for Bacteremia Prevention in Post Cardiac Surgical Intensive Care Unit Patients https://ClinicalTrials.gov/show/NCT03309137 Recruiting Hamilton Health Sciences Corporation 2019-09-30
NCT03248063 Non-inferiority Trial Comparing Cloxacillin vs Cefazolin in Methicillin-susceptible Staphylococcus Aureus Bacteremia https://ClinicalTrials.gov/show/NCT03248063 Recruiting Assistance Publique - Hôpitaux de Paris 2022-06-30
NCT03218397 Rapid Identification and Phenotypic Susceptibility Testing for Gram-Negative Bacteremia https://ClinicalTrials.gov/show/NCT03218397 Completed Duke University 2018-11-03
NCT03182465 Predictive Value of ProCalcitonin for the Detection of Bacteraemia in Patients Presenting to the Emergency Department for Low Risk Chemo-induced Febrile Neutropenia https://ClinicalTrials.gov/show/NCT03182465 Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2020-08-25
NCT03163446 Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia https://ClinicalTrials.gov/show/NCT03163446 Completed ContraFect 2019-03-07
NCT03162250 Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Participants With Staphylococcus Aureus Bacteremia Receiving Standard-of-Care (SOC) Antibiotics https://ClinicalTrials.gov/show/NCT03162250 Completed Genentech, Inc. 2020-01-15
NCT03101072 Antibiotic Durations for Gram-negative Bacteremia https://ClinicalTrials.gov/show/NCT03101072 Completed University of Geneva, Switzerland 2019-06-11
NCT03089697 Phase IIa Clinical Study of N-Rephasin® SAL200 https://ClinicalTrials.gov/show/NCT03089697 Recruiting Intron Biotechnology, Inc. 2020-01-31
NCT03005145 Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness https://ClinicalTrials.gov/show/NCT03005145 Recruiting Sunnybrook Health Sciences Centre 2022-03-31
NCT02972983 Daptomycin as Adjunctive Therapy for Staphylococcus Aureus Bacteremia https://ClinicalTrials.gov/show/NCT02972983 Completed McGill University Health Centre/Research Institute of the McGill University Health Centre 2019-07-31
NCT02917551 BALANCE on the Wards: A Pilot RCT https://ClinicalTrials.gov/show/NCT02917551 Recruiting Sunnybrook Health Sciences Centre 2020-01-10
NCT02914132 Safety Evaluation of Seraph® 100 to Reduce Bacteremia in Patients on Hemodialysis https://ClinicalTrials.gov/show/NCT02914132 Completed ExThera Medical Corporation 2018-06-07
NCT02795949 Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae https://ClinicalTrials.gov/show/NCT02795949 Recruiting Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 2020-01-31
NCT02789501 Comparison of a TauroLockâ„¢ Based Regimen to 4% Citrate as Lock Solution in Tunneled Haemodialysis Catheters for the Prevention of Bacteraemia and Dysfunction https://ClinicalTrials.gov/show/NCT02789501 Completed Medical University of Vienna 2016-08-31
NCT02784821 Antibiotic “Dysbiosis” in Preterm Infants https://ClinicalTrials.gov/show/NCT02784821 Completed University of Florida 2019-09-11
NCT02783404 An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Dental Procedures https://ClinicalTrials.gov/show/NCT02783404 Recruiting University of Santiago de Compostela 2018-12-31
NCT02743585 Impact of Rapid Pathogen Identification From Blood Cultures (RABbIT) https://ClinicalTrials.gov/show/NCT02743585 Active, not recruiting Tan Tock Seng Hospital 2019-07-02
NCT02660346 IL-10 Stratifying Tool for Towards Antibiotic Selection for MRSaB https://ClinicalTrials.gov/show/NCT02660346 Completed Sharp HealthCare 2017-09-15
NCT02633124 Preventing Catheter-related Bacteremia When Administering Injectable Medications in Premature Infants. https://ClinicalTrials.gov/show/NCT02633124 Recruiting University Hospital, Lille 2020-05-31
NCT02538159 Safety and Bacteraemia Between Peripherally Inserted and Central Inserted Catheters. https://ClinicalTrials.gov/show/NCT02538159 Completed Fundació Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau 2017-06-11
NCT02536352 Effect of Supplementation of Fluoride on Maternal Periodontal Health, Preterm Delivery, and Perinatal Well-Being https://ClinicalTrials.gov/show/NCT02536352 Completed Johns Hopkins University 2019-10-01
NCT02516514 The Only Blood Culture for Diagnosis of Bacteremia - Comparative Study of Practice https://ClinicalTrials.gov/show/NCT02516514 Completed University Hospital, Caen 2012-12-31
NCT02439359 A Placebo-Controlled, Dose-Escalating Study to Examine the Safety and Tolerability of Single Intravenous Doses of CF-301 in Healthy Subjects https://ClinicalTrials.gov/show/NCT02439359 Completed ContraFect 2015-12-31
NCT02386592 Prevention of Nosocomial Bacteremia Among Zambian Neonates https://ClinicalTrials.gov/show/NCT02386592 Completed Boston University 2017-04-15
NCT02357966 A Study of the Safety and Efficacy of 514G3 in Subjects Hospitalized With Bacteremia Due to Staphylococcus Aureus https://ClinicalTrials.gov/show/NCT02357966 Completed XBiotech, Inc. 2017-01-31
NCT02261506 Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness: A Pilot RCT https://ClinicalTrials.gov/show/NCT02261506 Completed Sunnybrook Health Sciences Centre 2017-08-30
NCT02215473 Bacteremia in Periodontal Patients https://ClinicalTrials.gov/show/NCT02215473 Completed University of Taubate 2013-12-31
NCT02210169 RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates https://ClinicalTrials.gov/show/NCT02210169 Completed Murdoch Childrens Research Institute 2018-04-30
NCT02208154 Ecological Effects of Decolonisation Strategies in Intensive Care https://ClinicalTrials.gov/show/NCT02208154 Completed UMC Utrecht 2017-10-27
NCT02168946 Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults https://ClinicalTrials.gov/show/NCT02168946 Completed Melinta Therapeutics, Inc. 2017-07-21
NCT02150031 Bacteraemia Secondary to Tooth Extraction: Chlorhexidine Prophylaxis Protocols https://ClinicalTrials.gov/show/NCT02150031 Completed University of Santiago de Compostela 2012-05-31
NCT02026895 Virulence of Staphylococcus Lugdunensis in Severe Infections https://ClinicalTrials.gov/show/NCT02026895 Completed University Hospital, Strasbourg, France 2016-02-29
NCT02115776 A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures https://ClinicalTrials.gov/show/NCT02115776 Completed University of Santiago de Compostela 2015-04-30
NCT01911624 Direct Thrombin Inhibitors Versus LMWH in Staphylococcus Aureus Bacteraemia https://ClinicalTrials.gov/show/NCT01911624 Completed Universitaire Ziekenhuizen Leuven 2016-04-30
NCT01898338 Efficacy of Daptomycin Plus Fosfomycin Versus Daptomycin for Treatment of MRSA Bacteremia https://ClinicalTrials.gov/show/NCT01898338 Completed Spanish Network for Research in Infectious Diseases 2018-01-10
NCT01737320 Duration of Antibiotics for the Treatment of Gram-negative Bacilli Bacteremia https://ClinicalTrials.gov/show/NCT01737320 Completed Rabin Medical Center 2018-03-31
NCT01728376 Safety & Efficacy of Daptomycin Versus Standard of Care (SOC) in 1 - 17 Year Olds With Staphylococcus Aureus Bacteremia (MK-3009-005) https://ClinicalTrials.gov/show/NCT01728376 Completed Cubist Pharmaceuticals LLC 2016-01-20
NCT01701219 Safety and Efficacy Study of Ceftaroline in Subjects With Staphylococcus Aureus Bacteremia or With Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia https://ClinicalTrials.gov/show/NCT01701219 Completed Forest Laboratories 2014-05-31
NCT01689753 Effect of the TEGO Connector in Preventing Tunneled Cuffed Hemodialysis Catheters From Dysfunction and/or Bacteremia https://ClinicalTrials.gov/show/NCT01689753 Completed Erasme University Hospital 2010-04-30
NCT01673269 Prospective Study of the Risk of Bacteremia in Directed Cholangioscopic Examination of the CBD https://ClinicalTrials.gov/show/NCT01673269 Completed Texas Tech University Health Sciences Center, El Paso 2013-10-31
NCT01647347 PVP Iodine Effect on Post Debridement Bacteraemia https://ClinicalTrials.gov/show/NCT01647347 Completed University of Zurich 2013-07-31
NCT01563406 Hub Cleansing to Prevent Hub Infection https://ClinicalTrials.gov/show/NCT01563406 Completed Rush University Medical Center 2013-06-30
NCT02024282 Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care https://ClinicalTrials.gov/show/NCT02024282 Completed KU Leuven 2014-12-31
NCT01450358 Evaluation in the Treatment of Nosocomial Sepsis Comparing Polymerase Chain Reaction With Conventional Blood Culture. https://ClinicalTrials.gov/show/NCT01450358 Completed Instituto do Coracao 2016-05-31
NCT01413555 Multicenter Blood Culture Quality Improvement https://ClinicalTrials.gov/show/NCT01413555 Completed Vanderbilt University 2013-03-31
NCT01394458 Efficacy and Safety of an Ethanol/Sodium Citrate Locking Solution: A Pilot Study https://ClinicalTrials.gov/show/NCT01394458 Completed University of Manitoba 2013-11-30
NCT01321879 Study to Evaluate the Safety and Efficacy of Telavancin in the Treatment of Gram Positive Bloodstream Infections in Cancer Patients https://ClinicalTrials.gov/show/NCT01321879 Completed M.D. Anderson Cancer Center 2016-12-31
NCT04207034 Effect of the Diode Laser on Bacteremia Associated With Periodontal Flap Surgery: A Clinico-Microbiological Study https://ClinicalTrials.gov/show/NCT04207034 Enrolling by invitation Krishnadevaraya College of Dental Sciences & Hospital 2020-04-30
NCT04160468 Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase https://ClinicalTrials.gov/show/NCT04160468 Recruiting ContraFect 2021-08-31
NCT04103203 Fast Assay for Pathogen Identification - Quasi-Experimental Intervention Study https://ClinicalTrials.gov/show/NCT04103203 Recruiting Hasselt University 2020-04-30
NCT04044703 Improving Dosing of Vancomycin in Young Infants With Infections https://ClinicalTrials.gov/show/NCT04044703 Recruiting Murdoch Childrens Research Institute 2020-08-31
NCT03976557 BIP CVC in Access Center at Danderyd Hospital, Stockholm, Sweden https://ClinicalTrials.gov/show/NCT03976557 Recruiting Bactiguard AB 2020-05-31
NCT03894046 Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus Complex https://ClinicalTrials.gov/show/NCT03894046 Recruiting Entasis Therapeutics 2020-07-19
NCT03876990 Clinical and Medico-economic Evaluation of a Rapid Test (ePlex-BCID®, GenMark) for the Diagnosis of Bacteremia and Fungemia. https://ClinicalTrials.gov/show/NCT03876990 Recruiting University Hospital, Grenoble 2020-12-31
NCT03714841 C-reactive Protein Information and Blood Cultures for Emergency Department Patients With Sepsis https://ClinicalTrials.gov/show/NCT03714841 Recruiting University of British Columbia 2019-09-15
NCT03671967 PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN) https://ClinicalTrials.gov/show/NCT03671967 Recruiting Rambam Health Care Campus 2024-01-31
NCT03643952 Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects With Complicated Skin and Soft Tissue Infections (cSSTI) and Bacteremia (MK-3009-029) https://ClinicalTrials.gov/show/NCT03643952 Completed Merck Sharp & Dohme Corp. 2020-04-07
NCT03627884 Outcomes of the Use of Sodium Bicarbonate (8.4%) Solution as a Catheter Lock Solution to Prevent Hemodialysis Catheter Loss Due to Lumen Clot Formation https://ClinicalTrials.gov/show/NCT03627884 Completed Coney Island Hospital, Brooklyn, NY 2018-03-30
NCT03611257 Effect of dRAST on Treatment for Bacteremia in Patients With Hematologic Diseases https://ClinicalTrials.gov/show/NCT03611257 Completed Seoul National University Hospital 2019-09-15
NCT03514446 Seven Versus Fourteen Days of Treatment in Uncomplicated Staphylococcus Aureus Bacteremia https://ClinicalTrials.gov/show/NCT03514446 Recruiting Hvidovre University Hospital 2021-05-01
NCT01266499 A Study Evaluating the Role of Oral Antibiotics in an Aim to Eradicate Carrier State of Carbapenem- Resistant Klebsiella Pneumonia (KPC). https://ClinicalTrials.gov/show/NCT01266499 Completed Rambam Health Care Campus 2011-01-31
NCT01243710 Taurolidine in Haemodialysis Catheter Related Bacteraemia https://ClinicalTrials.gov/show/NCT01243710 Completed Imperial College Healthcare NHS Trust 2012-12-31
NCT01216761 A Cluster-randomized Cross-over Trial Evaluating the Comparative Effectiveness of Three Skin Antiseptic Interventions https://ClinicalTrials.gov/show/NCT01216761 Completed University of Michigan 2009-09-30
NCT01023555 Increasing the Yield of Blood Cultures in Neonates https://ClinicalTrials.gov/show/NCT01023555 Completed Shaare Zedek Medical Center 2010-07-31
NCT00973063 Effectiveness of Routine Sterile Gloving in Blood Culture https://ClinicalTrials.gov/show/NCT00973063 Completed Seoul National University Hospital 2009-12-31
NCT00889564 HeRO Vascular Access Device Bacteremia Study https://ClinicalTrials.gov/show/NCT00889564 Completed Merit Medical Systems, Inc. 2007-03-31
NCT04146922 Switch to Oral Antibiotics in Gram-negative Bacteremia https://ClinicalTrials.gov/show/NCT04146922 Recruiting Hamad Medical Corporation 2022-09-30
NCT04291768 Shortened Antibiotic Treatment of 5 Days in Gram-negative Bacteremia https://ClinicalTrials.gov/show/NCT04291768 Recruiting Hvidovre University Hospital 2023-10-01
NCT02476487 The Benefit of FDG PET CT in the Treatment Algorithm of Staphylococcus Aureus Bacteremia https://ClinicalTrials.gov/show/NCT02476487 Active, not recruiting Rambam Health Care Campus 2019-05-31
NCT01898208 Rapid Identification and Susceptibility Testing of Pathogens From Blood Cultures https://ClinicalTrials.gov/show/NCT01898208 Completed Mayo Clinic 2014-08-31
NCT03761953 Oritavancin for Staphylococcus Aureus Infections in Opioid Users https://ClinicalTrials.gov/show/NCT03761953 Recruiting University of Pennsylvania 2019-12-31
NCT03138733 Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia https://ClinicalTrials.gov/show/NCT03138733 Recruiting Basilea Pharmaceutica 2021-08-31
NCT00735813 Taurolidine Lock Solution in the Prevention of Catheter Related Bacteremia https://ClinicalTrials.gov/show/NCT00735813 Completed Aarhus University Hospital 2012-09-30
NCT00692848 Impact of Procalcitonin on the Management of Children Aged 1 to 36 Month Presenting With a Fever Without a Source https://ClinicalTrials.gov/show/NCT00692848 Completed St. Justine’s Hospital 2007-11-30
NCT00646399 Safety and Efficacy of Pagibaximab Injection in Very Low Birth Weight Neonates for Prevention of Staphylococcal Sepsis https://ClinicalTrials.gov/show/NCT00646399 Completed Biosynexus Incorporated 2011-05-31
NCT00614679 A Novel Catheter Lock Solution for Treatment of Tunneled Hemodialysis Catheter-Associated Bacteremia https://ClinicalTrials.gov/show/NCT00614679 Completed University of California, San Diego 2008-12-31
NCT00609375 Efficacy of Cefepime Continuous Infusion Versus an Intermittent Dosing Regimen https://ClinicalTrials.gov/show/NCT00609375 Completed Javeriana University 2007-12-31
NCT00571259 Prophylactic Antimicrobial Catheter Lock https://ClinicalTrials.gov/show/NCT00571259 Completed Satellite Healthcare 2010-01-31
NCT00555282 Rate of Catheter Colonization and Risk of Bloodstream Infection During Use of Two Different Central Venous Catheters (CVC) https://ClinicalTrials.gov/show/NCT00555282 Completed B. Braun Melsungen AG 2009-07-31
NCT00515151 Prevention of Catheter-Associated Infection With the Skin Disinfectant Octenidine Dihydrochloride https://ClinicalTrials.gov/show/NCT00515151 Completed University Hospital Freiburg NA
NCT00454285 Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing https://ClinicalTrials.gov/show/NCT00454285 Completed Atrium Health 2005-11-30
NCT00417235 Dressing: Frequency of Change and Evaluation of an Antiseptic-Impregnated Catheter Dressing in ICU Patients https://ClinicalTrials.gov/show/NCT00417235 Completed University Hospital, Grenoble 2008-06-30
NCT00406198 Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis https://ClinicalTrials.gov/show/NCT00406198 Completed Hopital Lariboisière NA
NCT00398411 Moxifloxacin in the Prevention of Bacteremia After High-dose Chemotherapy and Transplantation of Peripheral Stem Cells https://ClinicalTrials.gov/show/NCT00398411 Completed University of Cologne 2008-12-31
NCT00235690 Optimizing Dosing of Colistin for Infections Resistant to All Other Antibiotics, Approved NIH Protocol Dated 12.06.07(DMID Protocol #07-0036) https://ClinicalTrials.gov/show/NCT00235690 Completed University of Pittsburgh 2015-08-31
NCT00198302 Clinical Trial Comparing Safety and Pharmacokinetics of Standard Antibiotic Therapy, Plus Aurexis® or Placebo, for Treatment of Staphylococcus Aureus Bacteremia (SAB) https://ClinicalTrials.gov/show/NCT00198302 Completed Bristol-Myers Squibb NA
NCT00138112 Trial of Prophylactic Versus Empirical Vancomycin for the Prevention of Streptococcal Sepsis After Hematopoietic Cell Transplantation https://ClinicalTrials.gov/show/NCT00138112 Completed Memorial Sloan Kettering Cancer Center NA
NCT00130221 Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections https://ClinicalTrials.gov/show/NCT00130221 Completed John H. Stroger Hospital NA
NCT00122642 Alcohol Locks for the Prevention of Tunneled Catheter-related Infections https://ClinicalTrials.gov/show/NCT00122642 Completed Erasmus Medical Center 2009-06-30
NCT00093067 Daptomycin in the Treatment of Subjects With Infective Endocarditis or Bacteremia Due to S. Aureus https://ClinicalTrials.gov/show/NCT00093067 Completed Cubist Pharmaceuticals LLC 2004-11-30
NCT00063089 Safety and Behavior of S. Aureus Immune Globulin Intravenous(Human), [Altastaph] in Patients With S. Aureus Bacteremia and Continuing Fever https://ClinicalTrials.gov/show/NCT00063089 Completed Nabi Biopharmaceuticals 2004-09-30
NCT00062647 Telavancin for Treatment of Uncomplicated Staphylococcus Aureus Bacteremia https://ClinicalTrials.gov/show/NCT00062647 Completed Cumberland Pharmaceuticals 2006-08-31
NCT00037050 Antibiotic Treatment for Infections of Short Term In-dwelling Vascular Catheters Due to Gram Positive Bacteria https://ClinicalTrials.gov/show/NCT00037050 Completed Pfizer NA
NCT00027248 Safety and Efficacy of MBI 226 for the Prevention of Central Venous Catheter-Related Bloodstream Infections https://ClinicalTrials.gov/show/NCT00027248 Completed BioWest Therapeutics Inc NA
NCT00002343 A Study of Rifabutin, Used Alone or With Ethambutol in the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in Patients With AIDS https://ClinicalTrials.gov/show/NCT00002343 Completed NIH AIDS Clinical Trials Information Service NA
NCT00002267 Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial https://ClinicalTrials.gov/show/NCT00002267 Completed NIH AIDS Clinical Trials Information Service NA
NCT00002192 Tolerance, Safety, and Activity of Rifapentine Alone and in Combination Therapy in AIDS Patients With Mycobacterium Avium Complex Bacteremia. https://ClinicalTrials.gov/show/NCT00002192 Completed NIH AIDS Clinical Trials Information Service NA
NCT00002101 A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo https://ClinicalTrials.gov/show/NCT00002101 Completed NIH AIDS Clinical Trials Information Service NA
NCT00002080 Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in HIV Positive Patients With CD4 Counts = or < 200: Treatment IND Study https://ClinicalTrials.gov/show/NCT00002080 Completed NIH AIDS Clinical Trials Information Service NA
NCT00002032 Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial https://ClinicalTrials.gov/show/NCT00002032 Completed NIH AIDS Clinical Trials Information Service NA
NCT00001995 A Double-Blind Randomized Clinical Trial of a Rifabutin Regimen in the Treatment of Mycobacterium-Avium Complex (MAC) Bacteremia in Patients With AIDS https://ClinicalTrials.gov/show/NCT00001995 Completed NIH AIDS Clinical Trials Information Service NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03356249 Next-Generation Sequencing Diagnostics of Bacteremia in Sepsis https://ClinicalTrials.gov/show/NCT03356249 Recruiting University Hospital Heidelberg 2020-12-31
NCT03248973 Successful Treatment of Maternal Listeria Monocytogenes Bacteremia in the First Trimester https://ClinicalTrials.gov/show/NCT03248973 Completed Far Eastern Memorial Hospital 2018-01-08
NCT03224052 Empirical ANtibiotic THErapy in Adults Hospitalised With Malaria https://ClinicalTrials.gov/show/NCT03224052 Completed Menzies School of Health Research 2017-10-31
NCT03208725 Childhood Acute Illness and Nutrition Network https://ClinicalTrials.gov/show/NCT03208725 Active, not recruiting University of Oxford 2020-01-31
NCT03176719 Non-specific Effects of Vaccination on Mortality and Morbidity https://ClinicalTrials.gov/show/NCT03176719 Active, not recruiting Radboud University 2017-10-31
NCT03148769 Spanish Bacteriemia Cohort 2016: Epidemiology, Clinical Management and Prognosis Factors https://ClinicalTrials.gov/show/NCT03148769 Completed Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 2017-05-31
NCT03096405 Impact MRSA -PCR on Patient Management https://ClinicalTrials.gov/show/NCT03096405 Completed Groupe Hospitalier Paris Saint Joseph 2016-03-31
NCT03039777 Procalcitonin Level as a Surrogate for Catheter-related Blood Stream Bacteremia Among Hemodialysis Patients https://ClinicalTrials.gov/show/NCT03039777 Completed Benha University 2017-02-28
NCT02988414 Diagnosis of Bacteremia/Septicemia and Culture Negative Endocarditis by the Karius Sequencing-Based Infectious Disease Diagnostic Assay https://ClinicalTrials.gov/show/NCT02988414 Completed Karius, Inc. 2017-04-30
NCT02979951 Fosfomycin i.v. for Treatment of Severely Infected Patients https://ClinicalTrials.gov/show/NCT02979951 Recruiting Infectopharm Arzneimittel GmbH 2020-06-30
NCT02869191 Blood Cultures’s Profitability in Intensive Care Unit https://ClinicalTrials.gov/show/NCT02869191 Completed Hospital Universitario Getafe 2015-11-30
NCT02852902 Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to ESBL- or Carbapenemase-producing Enterobacterales in Solid Organ Transplantation: an Observational Multinational Study. https://ClinicalTrials.gov/show/NCT02852902 Completed Spanish Network for Research in Infectious Diseases 2016-10-31
NCT02774850 Home Away From Home - Medical Outcomes https://ClinicalTrials.gov/show/NCT02774850 Completed Children’s Hospital of Philadelphia 2019-07-26
NCT02719769 Clinical Performance of the Accelerate ID/AST System for Positive Blood Culture https://ClinicalTrials.gov/show/NCT02719769 Completed Accelerate Diagnostics, Inc. 2016-05-31
NCT02599220 Clinical Outcomes and Cost of Gram Negative Bacteremia https://ClinicalTrials.gov/show/NCT02599220 Completed Duke University 2015-05-31
NCT02543957 Factors Associated With Increased Risk of Bacteremia and Cholangitis in ERCP With Cholangioscopy https://ClinicalTrials.gov/show/NCT02543957 Recruiting Baylor College of Medicine 2020-09-30
NCT02535468 T2Bacteria Panel Pivotal Study https://ClinicalTrials.gov/show/NCT02535468 Completed T2 Biosystems 2016-04-30
NCT02482051 Ultra Rapid Culture Independent Detection of High-Priority Carbapenem Resistant Enterobacteriaceae Directly From Blood https://ClinicalTrials.gov/show/NCT02482051 Enrolling by invitation Denver Health and Hospital Authority 2021-01-31
NCT02420366 Study of Cases of Serious Infections Due to Carbapenem-Resistant Enterobacteriaceae https://ClinicalTrials.gov/show/NCT02420366 Completed Melinta Therapeutics, Inc. 2015-01-31
NCT02005159 Study of the Impact of the Minimum Inhibitory Concentration and Susceptible Cut-off Points (CLSI, EUCAST, and Pharmacokinetics/Pharmacodynamics)in Prognosis of Bacteremia by Enterobacteriaceae https://ClinicalTrials.gov/show/NCT02005159 Completed Andalusian Network for Design and Translation of Advanced Therapies 2014-12-31
NCT01971762 Staphylococcus Aureus Bacteremia: Impact of an Intervention Program in Improving the Clinical Management and Review of the Clinical and Molecular Epidemiology https://ClinicalTrials.gov/show/NCT01971762 Completed Andalusian Network for Design and Translation of Advanced Therapies 2011-10-31
NCT01961206 Community-Onset Bacteremia Due to ESBL Producing E.Coli or K.Pneumoniae in China: Prevalence, Risk Factors and Prognosis https://ClinicalTrials.gov/show/NCT01961206 Completed Sir Run Run Shaw Hospital 2014-11-30
NCT01919762 Detecting Infections Rapidly and Easily for Bacteremia Trial (DIREBT) https://ClinicalTrials.gov/show/NCT01919762 Completed T2 Biosystems 2015-08-31
NCT01917461 Observational, Prospective Clinical Study to Evaluate Biomarkers as Indicators of Acute Bacterial or Viral Infections https://ClinicalTrials.gov/show/NCT01917461 Completed MeMed Diagnostics Ltd. 2013-12-31
NCT01879761 Immune Resolution After Staphylococcus Aureus Bacteremia https://ClinicalTrials.gov/show/NCT01879761 Recruiting University of Chicago 2019-12-31
NCT01867905 Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT01867905 Completed University of British Columbia 2018-09-05
NCT02025699 Prospective Study to Characterize Host-pathogen Related Factors in Hospitalized and ED Patients With LRTI and/or Sepsis https://ClinicalTrials.gov/show/NCT02025699 Completed MeMed Diagnostics Ltd. 2016-06-30
NCT01764490 Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to Extended-spectrum Beta-lactamase (ESBL) or Carbapenemase-producing Enterobacteriaceae: an Observational Multinational Study https://ClinicalTrials.gov/show/NCT01764490 Completed Spanish Network for Research in Infectious Diseases 2013-12-31
NCT01551667 Immune Response of Patients With Chronic, Staphylococcus Aureus-infected Wounds https://ClinicalTrials.gov/show/NCT01551667 Completed Centre Hospitalier Universitaire de NÄ«mes 2016-03-31
NCT01410578 The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUO https://ClinicalTrials.gov/show/NCT01410578 Completed Chinese PLA General Hospital 2011-03-31
NCT01359891 Clinical Evaluation of Novel Biomarkers in Patients With Septicemia https://ClinicalTrials.gov/show/NCT01359891 Recruiting Medical University of Graz 2020-10-31
NCT04295915 Clinical Performance and Reproducibility of the Accelerate PhenoTestâ„¢ Blood Culture (BC) Kit With New Antibiotic Wave I Updates https://ClinicalTrials.gov/show/NCT04295915 Recruiting Accelerate Diagnostics, Inc. 2020-06-30
NCT04147975 Assessment of Assay for Rapid Identification of Bloodstream Infections From Whole Blood https://ClinicalTrials.gov/show/NCT04147975 Recruiting HelixBind, Inc. 2020-09-30
NCT04055922 Comparison of Solid Organ Transplant https://ClinicalTrials.gov/show/NCT04055922 Enrolling by invitation Methodist Health System 2020-05-31
NCT04042636 Epidemiologic Patterns of Bacteremia After Trauma https://ClinicalTrials.gov/show/NCT04042636 Completed Asan Medical Center 2015-12-31
NCT04008446 Effect of Vitamin B12 on the Development of Sepsis, in Culture Positive Patients https://ClinicalTrials.gov/show/NCT04008446 Recruiting University of Zurich 2020-11-01
NCT03925402 Ertapenem for Initial Empirical Treatment of Third Generation Cephalosporin Resistant Enterobacteriaceae Bacteremia https://ClinicalTrials.gov/show/NCT03925402 Recruiting Phramongkutklao College of Medicine and Hospital 2023-01-01
NCT03908086 Bloodstream Infections in Patients With Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT03908086 Completed Rigshospitalet, Denmark 2017-12-31
NCT03765749 Empirical Antibiotic and Outcome in Community-onset Bacteremia https://ClinicalTrials.gov/show/NCT03765749 Recruiting Phramongkutklao College of Medicine and Hospital 2020-12-01
NCT03597841 Turkish Prospective Cohort Study on Carbapenem Resistant Klebsiella Pneumonia Bacteremia https://ClinicalTrials.gov/show/NCT03597841 Completed Koç University 2019-06-25
NCT03577366 Prevalence and Characterization of Diagnostic Error Among Patients With Bacteremia https://ClinicalTrials.gov/show/NCT03577366 Completed University of Ottawa 2017-08-13
NCT03497741 Predictive Value of Procalcitonin for Bacteremia in the ICU https://ClinicalTrials.gov/show/NCT03497741 Recruiting Rijnstate Hospital 2019-04-01
NCT03441126 Blood Culture Improvement Guidelines and Diagnostic Stewardship for Antibiotic Reduction in Critically Ill Children https://ClinicalTrials.gov/show/NCT03441126 Active, not recruiting Johns Hopkins University 2021-04-30
NCT01198262 Rapid Test to Detect Staphylococcus Aureus in Blood and Wound Infections https://ClinicalTrials.gov/show/NCT01198262 Completed VA Medical Center, Houston 2009-08-31
NCT01184339 Prospective Study Into the Performance of the MicroPhage S. Aureus/MSSA/MRSA Test Direct From Blood Culture Positives https://ClinicalTrials.gov/show/NCT01184339 Completed MicroPhage, Inc. 2010-01-31
NCT01039259 The Impact of Material on Microbiota in Association With Tongue and Lip Piercing https://ClinicalTrials.gov/show/NCT01039259 Completed Medical University Innsbruck 2009-02-28
NCT04070820 Combination Treatment for Enterococcus Faecalis Bacteriemia Multicenter, Observational Study" https://ClinicalTrials.gov/show/NCT04070820 Recruiting University of Bologna 2021-03-31
NCT01179022 Incidence of Bacteremia Following Argon Plasma Coagulation in Patients With Endobronchial Lesions https://ClinicalTrials.gov/show/NCT01179022 Completed Meir Medical Center 2012-10-31
NCT00814151 MicroPhage S. Aureus / MSSA / MRSA Blood Culture Beta Trial https://ClinicalTrials.gov/show/NCT00814151 Completed MicroPhage, Inc. 2008-12-31
NCT03841162 Fast Assay for Pathogen Identification and Characterization https://ClinicalTrials.gov/show/NCT03841162 Completed Hasselt University 2020-04-17
NCT00714402 Procalcitonin Level and Kinetics in Children With Bacterial Infections https://ClinicalTrials.gov/show/NCT00714402 Completed Shaare Zedek Medical Center NA
NCT00548002 Combination Therapy With Fluoroquinolone in Staphylococcus Aureus Bacteremia https://ClinicalTrials.gov/show/NCT00548002 Completed University of Helsinki NA
NCT00448942 The Impact of Chlorhexidine-Based Bathing on Nosocomial Infections https://ClinicalTrials.gov/show/NCT00448942 Completed Hunter Holmes Mcguire Veteran Affairs Medical Center NA
NCT00414362 Clinical Impact of Fluoroquinolone Resistance in Bacteremia Caused by Gram-Negative Bacilli of Urinary Tract Origin https://ClinicalTrials.gov/show/NCT00414362 Completed University of Pittsburgh 2017-06-30
NCT00414193 Piperacillin/Tazobactam for Bacteremia With Organisms Producing Chromosomally-Encoded AmpC Beta-Lactamase https://ClinicalTrials.gov/show/NCT00414193 Completed University of Pittsburgh 2017-12-31
NCT00965198 Comparison of Infection Rates Among Patients Using Two Catheter Access Devices https://ClinicalTrials.gov/show/NCT00965198 Completed Emory University 2011-07-31
NCT00319826 Virulence Determinants in S Aureus Bacteremia https://ClinicalTrials.gov/show/NCT00319826 Completed Duke University 2013-08-31
NCT00304902 Chart Review of Outcome of Treatment for S. Aureus Bacteremia https://ClinicalTrials.gov/show/NCT00304902 Completed VA Medical Center, Houston 2010-07-31
NCT00177957 Gram Negative Bacteremia, Risk Factors for Failure of Therapy https://ClinicalTrials.gov/show/NCT00177957 Completed University of Pittsburgh 2016-05-31
NCT00798330 Dental Study in Cancer Patients With Central Venous Catheters https://ClinicalTrials.gov/show/NCT00798330 Completed UConn Health 2012-12-31
NCT00177736 Pharmacodynamic Parameters of Two Different Doses of Cefepime https://ClinicalTrials.gov/show/NCT00177736 Completed University of Pittsburgh NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT04410276 VENOUS: A Translational Study of Enterococcal Bacteremia https://ClinicalTrials.gov/show/NCT04410276 Recruiting The University of Texas Health Science Center, Houston 2025-05-31
NCT03937245 Epidemiology and Determinants of Outcomes of Hospital Acquired Blood Stream Infections in the Intensive Care https://ClinicalTrials.gov/show/NCT03937245 Recruiting Outcome Rea 2020-11-01